A Novel PAX9 Mutation in a Family with Non-Syndromic Oligodontia
نویسندگان
چکیده
منابع مشابه
A novel mutation in human PAX9 causes molar oligodontia.
Experimental and animal studies, as well as genetic mutations in man, have indicated that the development of dentition is under the control of several genes. So far, mutations in MSX1 and PAX9 have been associated with dominantly inherited forms of human tooth agenesis that mainly involve posterior teeth. We identified a large kindred with several individuals affected with molar oligodontia tha...
متن کاملA Novel AXIN2 Missense Mutation Is Associated with Non-Syndromic Oligodontia
Oligodontia is defined as the congenital absence of six or more permanent teeth, excluding the third molars. Oligodontia may contribute to masticatory dysfunction, speech alteration, aesthetic problems and malocclusion. Numerous gene mutations have been association with oligodontia. In the present study, we identified a de novo AXIN2 missense mutation (c.314T>G) in a Chinese individual with non...
متن کاملNon-syndromic oligodontia: a case report.
BACKGROUND oligodontia is a condition with developmental absence of six or more permanent teeth excluding the third molars. It is a rare finding which has not been frequently documented in Nigerian children. OBJECTIVE to report a case of non syndromic oligodontia. METHODS The details of the clinical presentation, course and outcome of a 9-year-old child with oligodontia were reviewed. The c...
متن کاملNon Syndromic Oligodontia: Case Report
Oligodontia is a rare genetic disorder which represents the congenital absence of more than six teeth in primary, permanent or both dentitions. It is usually a part of a syndrome and seldom occurs as an isolated entity. Genes responsible for non syndromic oligodontia are found to be MSX1 and PAX9 genes. In this case report a 13 year old boy is presented who had absence of all four second perman...
متن کاملRehabilitation of a patient with non-syndromic partial oligodontia
Oligodontia is defined as a congenital tooth agenesis with the absence of six or more permanent teeth. This clinical report describes a patient with non-syndromic partial oligodontia, with retained deciduous teeth and the absence of 16 permanent teeth. Anterior esthetic problems were caused by interarch tooth size discrepancy, interdental space, aberrant tooth dimensions, and the absence of cen...
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ژورنال
عنوان ژورنال: THE JOURNAL OF THE KOREAN ACADEMY OF PEDTATRIC DENTISTRY
سال: 2016
ISSN: 1226-8496,2288-3819
DOI: 10.5933/jkapd.2016.43.3.299